Data/hora: 12/05/2024 12:20:22

Biblioteca(s): 	Embrapa Agroindústria de Alimentos; Embrapa Pecuária Sudeste.	
Data corrente: 	20/02/2018	
Data da última atualização: 	03/09/2018	
Autoria: 	POLITI, F. A. S.; SOUZA JUNIOR, A. A.; FANTATTO, R. R.; PIETRO, R. C. L. R.; BARIONI JUNIOR, W.; RABELO, M. D.; BIZZO, H. R.; CHAGAS, A. C. de S.; FURLAN, M.	
Afiliação: 	Flavio Augusto Sanches Politi, UNESP; Amauri Alves Souza Junior, UNESP; Rafaela Regina Fantatto, UNESP; Rosemeire Cristina Linhari Rodrigues Pietro, UNESP; WALDOMIRO BARIONI JUNIOR, CPPSE; MARCIO DIAS RABELO, CPPSE; HUMBERTO RIBEIRO BIZZO, CTAA; ANA CAROLINA DE SOUZA CHAGAS, CPPSE; Maysa Furlan, UNESP.	
Título: 	Chemical composition and in vitro anthelmintic activity of extracts of tagetes patula against a multidrug-resistant isolate of Haemonchus contortus.	
Ano de publicação: 	2018	
Fonte/Imprenta: 	Chemistry & Biodiversity, 2018, v.15, n.2, 2018.	
Páginas: 	10 p.	
DOI: 	10.1002/cbdv.201700507	
Idioma: 	Inglês	
Conteúdo: 	Sheep breeding has suffered economic losses due to parasitism by gastrointestinal nematodes, particularly Haemonchus contortus. The use of natural products, specifically Tagetes patula, has been suggested as an alternative method of combatting this issue. Chemical analyses of the extracts of this species described in the literature report the presence of important classes of secondary metabolites such as thiophenes, flavonoids, alkaloids, and benzofurans, some of which were identified and isolated in this study. The aim of this work was to test the effect of the essential oil (EO) and the ethanolic extract of the aerial parts (TpEtOH ) of T. patula on eggs and larvae of H. contortus, through an egg hatch test (EHT) and a larval development test (LDT). In the EHT, the EO showed 100% inhibition at 0.75 mg mL-1 (LC50 = 0.0780 mg mL-1 ), and the TpEtOH showed 100% inhibition at 100 mg mL-1 (LC50 = 12.8 mg mL-1 ). In the LDT, the EO showed 100% inhibition at 0.375 mg mL-1 (LC50 = 0.0400 mg mL-1 ), and the TpEtOH showed 100% inhibition at 1.56 mg mL-1 (LC50 = 0.340 mg mL-1 ). Compared to available literature data, the results presented here suggest that the crude extracts of T. patula have substantial potential for controlling this nematode by interrupting its life cycle and/or preventing it from reaching the infective stage.	
Palavras-Chave: 	Natural products.	
Thesagro: 	Haemonchus Contortus; Tagetis patula.	
Thesaurus Nal: 	Haemonchus; Tagetes patula; terpenoids; thiophenes.	
Categoria do assunto: 	X Pesquisa, Tecnologia e Engenharia	
Registro original: 	Embrapa Pecuária Sudeste (CPPSE)	
Exemplares: 	CTAA - (14092-1) - UPC - AP - DD -  -  -  - DIS
CPPSE - (24343-1) - UPC - AP - DD - PROCI-2018.00014 - POL - 2018.00017 - DIS